Protease Inhibitors and Phosphatase Inhibitors
Abcam MMP12 Inhibitor Screening Assay Kit (Colorimetric).
MMP12 Inhibitor Screening Assay Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Ihmt-PI3Kδ-372 | 2429889-61-0 | 99.7% | C26H23F2N7O2 | 10MG
IHMT-PI3Kδ-372 is a potent, selective small-molecule inhibitor of PI3Kδ used in preclinical research. It demonstrates nanomolar potency against PI3Kδ and has documented selectivity, solubility, and storage properties for in vitro and in vivo experiments.
- Potent PI3Kδ inhibition (IC50 14 nM).
- High selectivity over other class I PI3Ks (56-83 fold).
- Minimal inhibition of several CYP enzymes (IC50s > 10 μM for CYP1A2, CYP2B6, CYP2C19, CYP3A4).
- High purity as analyzed by supplier (≈99.7%).
- Soluble in DMSO (50 mg/mL) and formulated for in vivo use (≥2.08 mg/mL with specified vehicles).
- White to off-white solid suitable for analytical and biological assays.
- Stable when stored as powder at recommended temperatures.
![Medchemexpress LLC 3-Isoxazolecarboxamide, 5-(2-furanyl)-N-[2-(1H-pyrazol-1-yl)ethyl]- | 943820-93-7 | 99.7% | C13H12N4O3 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 3-Isoxazolecarboxamide, 5-(2-furanyl)-N-[2-(1H-pyrazol-1-yl)ethyl]- | 943820-93-7 | 99.7% | C13H12N4O3 | 50 MG
Wnt/β-catenin agonist 2 is a potent Wnt agonist that activates Wnt/β-catenin signaling. It can be used in the research of diseases related to signal transduction.
- Activates Wnt/β-catenin signaling
- Potent Wnt agonist
- Used in research of diseases related to signal transduction
- Activator for β-Catenin in SW480 cell line
- Influences differentiation of ST2 cells into osteoblasts
- White to off-white solid
Cayman Chemical DXR InhIbItr 11asodIum sal 1mg
An inhibitor of P. falciparum DXR (IC50 = 0.11 µM); inhibits the growth of P. falciparum in isolated human erythrocytes (IC50 = 0.37 µM)
Selleck Chemical LLC P5091 (P005091) 10mg 882257-11-6
P5091(P005091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 ?M and the closely related USP47. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical Syk InhIbItr 1mg
An oxindole compound that potently blocks Syk activity (IC50 = 14 nM) and inhibits FcεRI-mediated rat RBL-2H3 basophil cell degranulation (EC50 = 313 nM); 2 μM completely abolishes convulxin-induced platelet aggregation and shape change
Abcam FAK Inhibitor 14 (mM/ml), FAK autophosphorylation inhibitor, 20MM_ML
MW 174.63 Da. Selective focal adhesion kinase (FAK) autophosphorylation inhibitor (IC₅₀ = 1 μM). No significant activity at other kinases including EGFR, PDGFR and IGF-RI. Increases cell detachment and inhibits cell adhesion in cancer cells. Anticancer agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical ENPP1 InhIbItr 4e 50mg
An ENPP1 inhibitor (IC50 = 0.188 µM); inhibits ENPP1 in MDA-MB-231 cells (IC50 = 0.732 µM); selectively cytotoxic to 4T1 murine metastatic breast cancer cells (IC50 = 2.99 µM) over non-cancerous L-02 and 293T cells at 50 µM; increases serum levels of IFN-β in mice when administered at a dose of 0.5 mg/kg in combination with cGAMP
Cayman Chemical PKR InhIbItr 25mg
Binds the ATP-binding site of PKR and blocks autophosphorylation (IC50 = 186-210 nM); protects neuroblastoma cells against cell damage triggered by ER stress; prevents phosphorylation of FADD, preventing apoptosis; reduces phosphorylation of PKR and eIF2α in the brain, enhancing long-term memory storage
Revvity Health Sciences Inc Tag-lite Adenosine A2B receptor Frozen & Labeled Cells, 200 Assay Points
Tag-lite Adenosine A2B receptor Frozen & Labeled Cells, 200 Assay Points
Apexbio Technology LLC Calpain Inhibitor II, ALLM, 5mg. Cas: 136632-32-1 MFCD: NA. Calpain inhibitor
Calpain inhibitor. Calpain Inhibitor II, ALLM 5mg. 136632-32-1.
Sigma Aldrich Fine Chemicals Biosciences Rat Fibroblast Growth Medium (500 ml) |
Rat Fibroblast Growth Medium (500 ml) |
Selleck Chemical LLC AZD7762 5mg 860352-01-8
AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM in a cell-free assay. It is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Z-VRPR-FMK (1 mg)
MALT1 inhibitor. The proteolytic activity of the paracaspase MALT1 is key to NF-κB and T cell activation. Z-VRPR-FMK is a selective MALT1 inhibitor of such proteolytic activity. Alternative Name: Z-Val-Arg-Pro-DL-Arg-FMK, MALT1 inhibitor. Formula: C31H49FN10O6. MW: 676.8. 114. Purity: ≥90% (HPLC). Sequence: Z-Val-Arg-Pro-DL-Arg-fluoromethylketone . TFA. Appearance: White to slightly yellow powder. Solubility: Soluble in water (1mg/ml). Long Term Storage: -20°C. Handling: Hygroscopic. Avoid freeze/thaw cycles.
Abcam O x amflatin, HDAC inhibitor, 1MG
MW 342.4 Da, Purity >95%. Potent mammalian HDAC inhibitor (IC₅₀ = 15.7 nM). Induces an elongated cell shape morphology with filamentous protrusions. Shows antiproliferative effects. Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement